Max Planck Research Group "Neuroanatomy & Connectivity"
The prefrontal cortex is a densely interconnected and functionally complex region that has evaded a coherent, generally accepted model of function. Our research agenda aims to characterize its connectivity and organization, and does so by branching into three interwoven topics:
cortical organization, primary as described by intrinsic functional connectivity;
its relationship to self-generated thought;
the modulation of functional brain organization by changes in higher-order internal frameworks that constitute an individual’s identity.
Our current line of research expands these themes to more generally investigate the emergence of network topology across association cortex. We integrate cortical surface mapping techniques with models of cortical development to explore how the morphology of the cortex gives rise to the network structures we observe.
Delineating the distinct cortical fields within the human prefrontal cortex (PFC), and their connectivity patterns, offers substantial challenges. Histological analysis of the macaque monkey PFC provides the gold standard for the cytoarchitectonic and connectional architecture [more]