Dr Elena Kleban | Probing the myelin water and venous compartments using non-linear signal phase evolution

Guest Lecture

  • Date: Sep 17, 2018
  • Time: 11:00 AM - 12:00 PM (Local Time Germany)
  • Speaker: Dr Elena Kleban
  • Research Associate School of Psychology (CUBRIC), Cardiff University, Cardiff, UK
  • Location: MPI for Human Cognitive and Brain Sciences
  • Room: Wilhelm Wundt Room (A400)
  • Host: Department of Neurophysics
Magnetic Resonance Imaging allows electromagnetic properties of the brain tissue to be measured in vivo, providing new markers of structure at a microscopic level. Evaluation of the local complex signal evolution observed using a multi-echo gradient-echo (mGRE) sequence can allow the electromagnetic and relaxivity properties of individual tissue compartments to be accessed. The phase evolution carries valuable information about the different compartments, but is dominated by non-local, large-length-scale field variations which present the main challenge in processing complex mGRE data. In my talk I will address the question of the origin of non-mono-exponential complex signal evolution from a mixed tissue and venous compartment and from white matter, respectively, and which exciting opportunities it may reveal in probing the brain microstructure.

Poster
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