Dr. Sofie Valk

Research group leader
Scientific representative

Main Focus

The central aim of my research is to understand the interplay between biological and social systems. Specifically, I focus on two interconnected objectives: (1) uncovering principles of brain organization, and (2) exploring how these principles relate to human cognition in health and disease. To achieve these goals, we develop and apply cutting-edge computational tools and methods. A particular focus of our work is the social domain, given its pivotal role in environmental input and its relevance to mental health. I integrate insights from diverse fields, including neuroscience, genetics, and psychology, into a cohesive framework that spans the lifespan and bridges neurodevelopmental and neurodegenerative processes.


Curriculum Vitae

Research positions
2024 - present
Lise Meitner Research Group Leader, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (W2)
2021 - present
Research Group Leader, 'Cognitive Neurogenetics,' INM-7, Forschungszentrum Jülich, Jülich, Germany
2020 - 2024
Otto Hahn Research Group Leader, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (W2)
Academic Education
2012 - 2017
Humboldt-Universität zu Berlin, Germany, Ph.D. in Psychology (summa cum laude)
2010 - 2012
University of Amsterdam, Netherlands, MSc in Brain and Cognitive Sciences
2005 - 2010
University of Amsterdam, Netherlands, BSc in BetaGamma
Double major: Artificial Intelligence and Philosophy
Keywords
Brain organization, neuropsychiatric conditions, genetic and metabolic underpinnings of brain function, brain development across the lifespan, social neuroscience, translation
Selected Publications
Valk, S. L., Xu, T., et al. (2022). Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex. Nature Communications, 13(1), 2341.
Wan, B., Hong, S. J., et al. (2023). Diverging asymmetry of intrinsic functional organization in autism. Molecular Psychiatry, 28(10), 4331-4341.
Serio, B., Hettwer, M. D., et al. (2024). Sex differences in functional cortical organization reflect differences in network topology rather than cortical morphometry. Nature Communications, 15(1), 7714.
Hettwer, M. D., Lariviere, S., et al. (2022). Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders. Nature Communications, 13(1), 6851. 

Full publication list on google scholar
Grants and Research Support
  • Lise Meitner Group, Max Planck Society (approx. €3,000,000)
  • Helmholtz International BigBrain Analytics (co-PI, €500,000 allocation)
  • Jacobs Research Fellowship (2025–2028, approx. €150,000)
  • Hector Foundation Research Development Award (2025–2030, approx. €150.000)
  • Otto Hahn Group, Max Planck Society (approx. €1,500,000)
Teaching Activities (Selection)
  • Biological Psychology, Bachelor of Psychology, Leipzig University
  • Cognitive Neuroscience MSc Seminar, Leipzig University
  • Translational Neuroscience Lecture Series, Heinrich Heine University Düsseldorf
Honors and awards
  • Hector Foundation Career Development Award (2025)
  • Jacobs Foundation Research Fellowship (2024)
  • Early Career Award, Deutsche Gesellschaft für Psychophysiologie (2022)
  • Otto Hahn Medal and Award (2018)
Professional Service
  • Educational Chair, Organization for Human Brain Mapping (2022–2025)
  • Co-chair, Enigma Gradients Working Group
  • Associate Editor: Brain Structure and Function, Aperture Neuro
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