It is widely known in neuroscience that males have larger brains than females on average. However, how the brain differs functionally between the sexes is less well understood.
Based on the premise that brain structure supports function, Bianca Serio and Sofie Valk from MPI CBS in Leipzig and Forschungszentrum Jülich investigated whether sex differences in the functional organization of the brain could be explained by differences in brain size, brain microstructure and the distance of functional connections along the cortical surface. Their results, recently published in the journal Nature Communications, suggest that sex differences in functional brain organization instead reflect small differences in functional networks and connections. In a second study published in Nature Communications, Svenja Küchenhoff from Sofie Valk's team was further able to show the extent to which sex hormones influence the structure of the brain.
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