Researchers for the first time compared schizophrenia and frontotemporal dementia, disorders that are both located in the frontal and temporal lobe regions of the brain. The idea can be traced back to Emil Kraepelin, who coined the term "dementia praecox" in 1899 to describe the progressive mental and emotional decline of young patients. His approach was quickly challenged, as only about 25 percent of those affected showed this form of disease progression. But now, with the help of imaging and machine learning, scientists have actually found the first valid indications of neuroanatomical patterns in the brain that resemble the signature of patients with frontotemporal dementia. Kraepelin was probably right in parts after all.