Publications of Patrick Freund

Bédard, S.; Valošek, J.; Seif, M.; Curt, A.; Schading-Sassenhausen, S.; Pfender, N.; Freund, P.; Hupp, M.; Cohen-Adad, J.: Normalizing spinal cord compression measures in degenerative cervical myelopathy. The Spine Journal (2025)

Lebret, A.; Frese, S.; Lévy, S.; Curt, A.; Callot, V.; Freund, P.; Seif, M.: Spinal cord blood perfusion deficit is associated with clinical impairment after spinal cord injury. Journal of Neurotrauma 42 (3-4), pp. 280 - 291 (2025)

Karthik, E. N.; Valosek, J.; Smith, A. C.; Pfyffer, D.; Schading-Sassenhausen, S.; Farner, L.; Weber II, K. A.; Freund, P.; Cohen-Adad, J.: SCIseg: Automatic segmentation of intramedullary lesions in spinal cord injury on T2-weighted MRI scans. Radiology: Artificial Intelligence 7 (1), e240005 (2025)

Weidner, N.; Abel, R.; Maier, D.; Röhl, K.; Röhrich, F.; Baumberger, M.; Hund-Georgiades, M.; Saur, M.; Benito, J.; Rehahn, K. et al.; Aach, M.; Badke, A.; Kriz, J.; Barkovits, K.; Killeen, T.; Farner, L.; Seif, M.; Hubli, M. H.; Marcus, K.; Maurer, M. A.; Robert, B.; Rupp, R.; Scheuren, P. S.; Schubert, M.; Schuld, C.; Sina, C.; Steiner, B.; Weis, T.; Hug, A.; Bolliger, M.; Weiskopf, N.; Freund, P.; Hothorn, T.; Schwab, M. E.; Curt, A.: Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: A randomised, double-blind, multicentre, placebo-controlled, phase 2b trial. Lancet Neurology 24 (1), pp. 42 - 53 (2025)

Schading-Sassenhausen, S.; Pfyffer, D.; Farner, L.; Grillhösl, A.; Mach, O.; Maier, D.; Grassner, L.; Leister, I.; Curt, A.; Freund, P.: Extent of traumatic spinal cord injury is lesion level dependent and predictive of recovery: A multicenter neuroimaging study. Journal of Neurotrauma 41 (17-18), pp. 2146 - 2157 (2024)

Pfyffer, D.; Smith, A. C.; Weber, K. A.; Grillhoesl, A.; Mach, O.; Draganich, C.; Berliner, J. C.; Tefertiller, C.; Leister, I.; Maier, D. et al.; Schwab, J. M.; Thompson, A.; Curt, A.; Freund, P.: Prognostic value of tissue bridges in cervical spinal cord injury: A longitudinal, multicentre, retrospective cohort study. Lancet Neurology 23 (8), pp. 816 - 825 (2024)

Freund, P.; Boller, V.; Emmenegger, T. M.; Akbar, M.; Hupp, M.; Pfender, N.; Wheeler‐Kingshott, C. A. M. G.; Cohen‐Adad, J.; Fehlings, M. G.; Curt, A. et al.; Seif, M.: Quantifying neurodegeneration of the cervical cord and brain in degenerative cervical myelopathy: A multicentre study using quantitativemagnetic resonance imaging. European Journal of Neurology 31 (7), e16297 (2024)

Pfender, N.; Jutzeler, C. R.; Hubli, M.; Scheuren, P. S.; Pfyffer, D.; Zipser, C. M.; Rosner, J.; Friedl, S.; Sutter, R.; Spirig, J. M. et al.; Betz, M.; Schubert, M.; Seif, M.; Freund, P.; Farshad, M.; Curt, A.; Hupp, M.: Potential thresholds of critically increased cardiac-related spinal cord motion in degenerative cervical myelopathy. Frontiers in Neurology 15, 1411182 (2024)

Büeler, S.; Freund, P.; Kessler, T. M.; Liechti, M. D.; David, G.: Improved inter-subject alignment of the lumbosacral cord for group-level in vivo gray and white matter assessments: A scan-rescan MRI study at 3T. PLOS ONE 19 (4), e0301449 (2024)

Emmenegger, T. M.; Pfyffer, D.; Curt, A.; Schading‐Sassenhausen, S.; Hupp, M.; Ashburner, J.; Friston, K.; Weiskopf, N.; Thompson, A.; Freund, P.: Longitudinal motor system changes from acute to chronic spinal cord injury. European Journal of Neurology 31 (4), e16196 (2024)

Lebret, A.; Lévy, S.; Pfender, N.; Farshad, M.; Altorfer, F. C. S.; Callot, V.; Curt, A.; Freund, P.; Seif, M.: Investigation of perfusion impairment in degenerative cervical myelopathy beyond the site of cord compression. Scientific Reports 13 (1), 22660 (2023)

Azzarito, M.; Emmenegger, T.; Ziegler, G.; Huber, E.; Grabher, P.; Callaghan, M. F.; Thompson, A.; Friston, K.; Weiskopf, N.; Killeen, T. et al.; Freund, P.: Coherent, time-shifted patterns of microstructural plasticity during motor-skill learning. NeuroImage 274, 120128 (2023)

Mehnert, U.; Walter, M.; Leitner, L.; Kessler, T. M.; Freund, P.; Liechti, M. D.; Michels, L.: Abnormal resting-state network presence in females with overactive bladder. Biomedicines 11 (6), 1640 (2023)

Pfyffer, D.; Zimmermann, S.; Şimşek, K.; Kreis, R.; Freund, P.; Seif, M.: Magnetic resonance spectroscopy investigation in the right human hippocampus following spinal cord injury. Frontiers in Neurology 14, 1120227 (2023)

Schading, S.; Seif, M.; Leutritz, T.; Hupp, M.; Curt, A.; Weiskopf, N.; Freund, P.: Reliability of spinal cord measures based on synthetic T1-weighted MRI derived from multiparametric mapping (MPM). NeuroImage 271, 120046 (2023)

Schading, S.; David, G.; Emmenegger, T. M.; Achim, C.; Thompson, A.; Weiskopf, N.; Curt, A.; Freund, P.: Dynamics of progressive degeneration of major spinal pathway following spinal cord injury: A longitudinal study. NeuroImage: Clinical 37, 103339 (2023)

Seif, M.; Leutritz, T.; Schading, S.; Emmengger, T.; Curt, A.; Weiskopf, N.; Freund, P.: Reliability of multi-parameter mapping (MPM) in the cervical cord: A multi-center multi-vendor quantitative MRI study. NeuroImage 264, 119751 (2022)

Büeler, S.; Yiannakas, M. C.; Damjanovski, Z.; Freund, P.; Liechti, M. D.; David, G.: Optimized multi-echo gradient-echo magnetic resonance imaging for gray and white matter segmentation in the lumbosacral cord at 3 T. Scientific Reports 12 (1), 16498 (2022)

David, G.; Vallotton, K.; Hupp, M.; Curt, A.; Freund, P.; Seif, M.: Extent of cord pathology in the lumbosacral enlargement in non-traumatic versus traumatic spinal cord injury. Journal of Neurotrauma 39 (9-10), pp. 639 - 650 (2022)

Schading, S.; Pohl, H.; Gantenbein, A.; Luechinger, R.; Sandor, P.; Riederer, F.; Freund, P.; Michels, L.: Tracking tDCS induced grey matter changes in episodic migraine: A randomized controlled trial. The Journal of Headache and Pain 22 (1), 139 (2021)