Stimulating your self...
Parkinson’s disease is a movement disorder that is related to dysfunctions in dopaminergic circuits. Frequently, it leads to cognitive deficits. The project explores effects of dopaminergic agents (L-DOPA) or deep brain stimulation on the blood oxygenation level dependent (BOLD) signal in Parkinson’s disease during a simple finger-tapping paradigm and in task-free situation (in order to investigate low-frequency oscillations). Here, we are cooperating with Robert Jech from the Department of Neurology at the Charles University in Prague.
R. Jech, D. Urgosik, J. Tintera, A. Nebuzelsky, J. Krasensky, R. Liscak, J. Roth, E. Ruzicka
Functional magnetic resonance imaging during deep brain stimulation: A pilot study in four patients with Parkinson's disease. Movement Disorders 16(2001): 1126-1132.