Equipped with state-of-the-art technology, we develop and optimize MRI pulse sequences to acquire quantitative MRI parameters at ultra-high resolutions. We work on reconstruction- and postprocessing algorithms to compensate for artifacts associated with high field strength MRI systems. These efforts include developing methods that handle physiological noise and head motion or designing schemes to reduce scan times. We also optimize the acquisition of data on highly specialized equipment, such as implementing spiral acquisition schemes for diffusion imaging on one of world-wide only three Connectom scanners, and of data for specific neuroscientific applications, such as functional imaging of the basal ganglia.

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DeepcomplexMRI deep learnig reconstruction has been modified to process multi-echo MRI images. First results for different undersampling strategies suggest that performance is comparable to modern iterative algorithms like ENLIVE while taking only about 5 minutes to reconstruct a full 3D 1mm³/voxel resolved head image stack. more

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We implemented and optimized kt-points RF pulses to reduce bias and shading artifacts in whole brain ultra-high resolution MPM. more

phase responses for GE-EPI for runs

In this project, we study the resolution limits of different high-resolution functional magnetic resonance imaging (fMRI) methods to resolve differences within the cerebral cortex. more

thresholded z-score maps of ODCs

In this project, we study the ability to image columnar structures in the human cerebral cortex using high-resolution functional magnetic resonance imaging (fMRI) methods at 7T. more

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Understanding brain development and decline is of utmost importance in an aging society. MRI Biophysics Research Group aims to uncover crucial mechanisms of human brain aging, by identifying the contribution of iron accumulation, a major determinant of brain development and brain decline. more

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