Enlightening the brain
Optical imaging (NIRS) has been introduced to cognitive neuroscience in recent years. It has decisive advantages in comparison with other imaging methods, namely easy application, insensitivity to movement artifacts and high temporal resolution. Accordingly, it is recommended for studies of cognitive neurodevelopment investigating neonates and children, and for researchers in psychiatry. We have developed various standard analysis approaches for this method, overcoming limitations such as the high variability of the so called “differential pathlength factor” (DPF). We investigated the reliability of the method and applied optical imaging in various studies including psychiatric and neurological patients (see also other projects). Furthermore, we explored the foundations of theneurovascular response (post-stimulus undershoot of the BOLD signal) with a multimodal imaging approach (plus fMRI).
Neurovascular coupling is impaired in cerebral microangiopathy – An event-related Stroop study. NeuroImage 34(2007): 26-34. IF 6.2
Corrigendum to Spontaneous slow hemodynamic oscillations are impaired in cerebral microangiopathy. Journal of Cerebral Blood Flow & Metabolism 27(2007): 1094.
Prefrontal brain activation during stop-signal response inhibition: An event-related functional near-infrared spectroscopy study.Behavioral Brain Research 176(2007): 259-266. IF 2.8
Enlightening the brain - Optical imaging in cognitive neuroscience. MPI Series in Cognitive Neuroscience, Leipzig, Germany, 2006. ISBN 3-936816-46-8.
Investigating the post-stimulus undershoot of the BOLD signal – a simultaneous fMRI and fNIRS study. NeuroImage 30(2006): 349-358. IF 6.2
Circadian variability is negligible in primary visual cortices as measured by fNIRS. International Journal of Psychophysiology 62(2006): 9-13. IF 2.6