Dr Ahmed A. Khalil | An update on resting-state functional MRI and cerebral hemodynamics

Recently, the use of resting-state functional MRI (rsfMRI) has been extended beyond the assessment of the brain’s functional organization to the monitoring of various aspects of cerebral hemodynamics. This has found practical applications in various disease states, particularly in cerebrovascular disorders, and has substantial methodological implications for the use of rsfMRI in clinical research. In this talk, I will: ● Discuss recent findings regarding the physiological sources and mechanisms of the components of the blood oxygenation level dependent (BOLD) signal that reflect the brain’s hemodynamic status ● Present recent methodological and practical developments to established rsfMRI-based methods for the assessment of blood flow within the brain ● Present some upcoming techniques for extracting hemodynamic parameters from rsfMRI data and their potential use in various diseases.