Using a field strength of 7 Tesla, the "Arterial Blood Contrast" (ABC), which is based on the Magnetization Transfer effect, could be measured with an isotropic spatial resolution of 1.5 mm in combination with a conventional functional MRI contrast.
In this project, we studied cortical myelin in living humans at the spatial scale of cortical columns using high-resolution quantitative magnetic resonance imaging (MRI) methods at 7 T.
In this project, we study the resolution limits of different high-resolution functional magnetic resonance imaging (fMRI) methods to resolve differences within the cerebral cortex.
We explore spatially resolved lipid imaging using matrix-assisted laser desorption/ionization (MALDI) as a method for validating MRI-based myelin biomarkers.
Embedded in the clinical trial NISCI (Nogo inhibition in spinal cord injury: www.nisci-2020.eu), we employ whole brain quantitative imaging at 3 Tesla as a new biomarker for de- and regeneration.
Columnar structures in the human visual cortex are studied using high-resolution fMRI methods in order to localize the actual source of neural processing more precisely.
We investigate the relationship between quantitative MRI (qMRI) at different cortical depths and cell counts, gene expression and white matter connections in the brain in order to provide novel biomarkers for tracking neurodegenerative diseases.
Robust U-fibre connectivity mapping can be achieved in vivo in the early visual processing stream using combined diffusion weighted imaging and functional retinotopy
In this project, we investigate the brains of wild chimpanzees who died of natural causes at different developmental stages using high-resolution quantitative MRI and histology.
Understanding brain development and decline is of utmost importance in an aging society. MRI Biophysics Research Group aims to uncover crucial mechanisms of human brain aging, by identifying the contribution of iron accumulation, a major determinant of brain development and brain decline.
