Bednarski, F. M.; Musholt, K.; Grosse Wiesmann, C.: Do infants have agency? The importance of control for the study of early agency. Developmental Review 64, 101022 (2022)
We work on improving reliability of quantitative parametric maps by correcting for rigid head motion and B0-fluctuations measured during acquisition at 7T as well as by employing general function approximators to correct for artifacts of unknown origin at 3T.
We performed laminar fMRI during a delayed match-to-sample task and varied working memory load and the requirement for a motor response. We found layer specific univariate and multivariate effects.
Columnar structures in the human visual cortex are studied using high-resolution fMRI methods in order to localize the actual source of neural processing more precisely.
A recent fMRI study showed layer-specific responses in the dorsolateral prefrontal cortex during a working memory task. We attempted to replicate the original findings using newly acquired data and a fully automated analysis.
In this project, we investigate the brains of wild chimpanzees who died of natural causes at different developmental stages using high-resolution quantitative MRI and histology.
Using a field strength of 7 Tesla, the "Arterial Blood Contrast" (ABC), which is based on the Magnetization Transfer effect, could be measured with an isotropic spatial resolution of 1.5 mm in combination with a conventional functional MRI contrast.
DeepcomplexMRI deep learnig reconstruction has been modified to process multi-echo MRI images. First results for different undersampling strategies suggest that performance is comparable to modern iterative algorithms like ENLIVE while taking only about 5 minutes to reconstruct a full 3D 1mm³/voxel resolved head image stack.
In this project, we studied cortical myelin in living humans at the spatial scale of cortical columns using high-resolution quantitative magnetic resonance imaging (MRI) methods at 7 T.
In this project, we study the resolution limits of different high-resolution functional magnetic resonance imaging (fMRI) methods to resolve differences within the cerebral cortex.
Understanding brain development and decline is of utmost importance in an aging society. MRI Biophysics Research Group aims to uncover crucial mechanisms of human brain aging, by identifying the contribution of iron accumulation, a major determinant of brain development and brain decline.